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Cancer Stem Cells Products
Cancers are chronologic diseases that seriously threaten human life. Many strategies have been developed for cancer treatment, including surgery, radiotherapy, chemotherapy, and targeted therapy. Because of all these treatments, however, traditional cancer treatment methods are effective only for some malignant tumors. The main reasons for the failure of cancer treatment are metastasis, recurrence, heterogeneity, resistance to chemotherapy and radiotherapy, and avoidance of immunological surveillance. All these failures could be explained by the characteristics of cancer stem cells (CSCs). CSCs can cause cancer relapse, metastasis, multidrug resistance, and radiation resistance through their ability to arrest in the G0 phase, giving rise to new tumors. Therefore, CSCs could be considered the most promising targets for cancer treatment. Cancer stem cells (CSCs) are cancer cells that possess characteristics associated with normal stem cells, specifically the ability to give rise to all cell types found in a particular cancer sample. CSCs are therefore tumorigenic (tumor-forming), perhaps in contrast to other non-tumorigenic cancer cells. CSCs may generate tumors through the stem cell processes of self-renewal and differentiation into multiple cell types. Such cells are hypothesized to persist in tumors as a distinct population and cause relapse and metastasis by giving rise to new tumors. Therefore, development of specific therapies targeted at CSCs holds hope for improvement of survival and quality of life of cancer patients, especially for patients with metastatic disease.High Impact List of Articles
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Synthesis and Characterization a New 1,3-Oxazepine Compounds from New Bis-4-Amino-3-mercapto-1,2,4-triazole Derivatives
Atyaf AQ Younus and Nasreen R JberOriginal Article: Organic Chemistry: An Indian Journal
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Synthesis and Characterization a New 1,3-Oxazepine Compounds from New Bis-4-Amino-3-mercapto-1,2,4-triazole Derivatives
Atyaf AQ Younus and Nasreen R JberOriginal Article: Organic Chemistry: An Indian Journal
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Structure simulation and study of electronic and dielectric properties of 1, 3-dimethyl urea
S.M.Devikarani,A.C.Ranjitha, H.R.SreepadOriginal Article: Organic Chemistry: An Indian Journal
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Structure simulation and study of electronic and dielectric properties of 1, 3-dimethyl urea
S.M.Devikarani,A.C.Ranjitha, H.R.SreepadOriginal Article: Organic Chemistry: An Indian Journal
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Synthesis, antimicrobial and cytotoxic activity of novel 4-phenoxy and 4-(substitutedamino) pyrazolo [3, 4-d] pyrimidine derivatives
Mohammed Kamal Abd El Hameid, Hala Bakr El-Nassan, Khaled Omar AhmedOriginal Article: Organic Chemistry: An Indian Journal
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Synthesis, antimicrobial and cytotoxic activity of novel 4-phenoxy and 4-(substitutedamino) pyrazolo [3, 4-d] pyrimidine derivatives
Mohammed Kamal Abd El Hameid, Hala Bakr El-Nassan, Khaled Omar AhmedOriginal Article: Organic Chemistry: An Indian Journal
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One-pot conversion of carboxylic acids into nitriles catalyzed by PEG 400 under microwave irradiation
Yu-Qing Cao, An-Li Qu, Rui-Yan Liu, Chun-Ming DuanOriginal Article: Organic Chemistry: An Indian Journal
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One-pot conversion of carboxylic acids into nitriles catalyzed by PEG 400 under microwave irradiation
Yu-Qing Cao, An-Li Qu, Rui-Yan Liu, Chun-Ming DuanOriginal Article: Organic Chemistry: An Indian Journal
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Microwave assisted synthesis of some new fluorine containing flavones and 1, 5-benzothiazipines
Majid I.amboli, Ramprasad A.Ghatul, Vijaykumar S.More, Yeshwant B.Vibhute -
Microwave assisted synthesis of some new fluorine containing flavones and 1, 5-benzothiazipines
Majid I.amboli, Ramprasad A.Ghatul, Vijaykumar S.More, Yeshwant B.Vibhute
