Abstract

Synthesis of 3-substituted quinazolinones as antifungal agents

Author(s): Chatrasal Singh Rajput, Sanjeev Sharma, Ashok Kumar

2-methyl-(3-sydnon-(3-yl))monosubstitutedquinazolin-4(3H)-one, 2-methyl- 3 –(sydnon-(4’-bromo-3’-yl))-monosubstitutedquinazolin-4(3H)-one,2- methyl-3-(sydnon-4-substitutedniline -3-yl)mono substituted quinazolin- 4 (3H) one were synthesized in present study. All the compounds have been screened for their anti-fungal activity. The structure of all by compounds was confirmed by their analytical (C, H, N) and spectral (IR, 1H NMR) data.


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