Liver plays a vital role in metabolism and excretion. Liver ailments needs to be treated with utmost care. In India, there are about 100 medicinal plants used in 33 herbal formulations. These hepatoprotective plants have the phytoconstituents such as phenyl compounds, coumarins, essential oils, monoterpenoids, diterpenoids, triterpenoids, steroids, alkaloids and other nitrogenous compounds. A brief review of phytoconstitments with hapatoprotective activity has been reported.