Improvement of drugs acting on central nervous system (CNS) will be technology constrained. The drugs with large particles cannot be delivered to brain owing to lack of functional platform for drug targeting. Around 1.5 billion individuals worldwide are experiencing different kind of neurological disorders. To overcome this issue pharmaceutical innovation is advancing producing the nanoparticles. Legitimate utilization of nanomedicines (nanoparticles) is one of the approaches to control the CNS illness all over world. Nanoparticles are particles between 1 nm to 100 nm in size. Nanotechnology is conceivable to convey the drugs to the particular site of the tissue across the Blood-Brain Barrier (BBB). Various sorts of nanoparticle are accessible for treatment of CNS diseases. These are polymer based nanoparticles, solid lipid nanoparticles, lipid based nanoparticles and many more.