Microbial transformation of S-(-)-Perillyl Alcohol by the filamentous fungi Fusarium verticillioides

Author(s): M. A.Aciar Roxana, Ravetti Soledad, Allendes Jorge, Rosa Melisa, Y.Hergert Lisandro, S.Bustos Pamela, G.Ortega María, G.Paraje María, A.Bustos Daniel

S-(-)-Perillyl alcohol (1) was transformed by Fusarium verticilloides over 7 days at 25°C to S-(-)-Perillyl aldehyde (2). Its structure was established by NMR spectroscopic and mass spectral studies. Total antioxidant potential and the radical-scavenging activity were determined by phosphomolybdenum and ABTS•+ assays, respectively. The results demonstrated that the oxidation of the primary alcohol of 1 had no effect on antioxidant activitywhen compared to startingmaterial and a reference compound. Obtaining derivatives of 1, is an important goal of research in microbial biotechnology and medicinal chemistry.

Share this       

Share this Page

Table of Contents

Scimago Journal Rank

SCImago Journal & Country Rank