The ground water quality of Tuljapur Taluka of Osmanabad district from Maharashtra (India) was evaluated during 2009-10. The parameters like temp, pH, TDS, conductivity, NO2, SO4, PO4 2-, D.O., C1-, CO2, MPN, Na+, K+, COD etc. were measured. The seasonal variation in these parameters is discussed here. All parameter were found to be within permissible limit. The MPN count was observed to be high in rainy season at two stations and in winter at S3.