All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.

Abstract

Four UV spectrophotometric methods for estimation of paliperidone in bulk and their pharmaceutical dosage form

Author(s): BhushanM.Firake,Harsha P.Bhutada,Rahul S.Talekar, DipakA.Korde

A simple, precise and economical methods of UV Spectrophotometry for the estimation of Paliperidone (PPD) in bulk and its formulation are proposed. PPD was estimated at 238.2nm, 236.8nm, 232nm, 232nm in ethanol, ethanol and distilled water, diethyl ether, diethyl ether and distilled water, respectively. The precision expressed as relative standard deviation, which was within 2.0 % for the above four methods. These shows linearity over the concentration range of 0.2-1µg/ml, 5-25µg/ml, 2-10µg/ ml, 10-100µg/ml with regression equation 0.018x + 0.004 (r2 = 0.999), 0.179x + 0.017 (r2 = 0.999), 0.180 + 0.042 (r2 = 0.998), 0.100x - 0.077 (r2 = 0.999). The proposed methods can be successfully applied for the determination of PPD in dosage forms.


Share this       
Awards Nomination 20+ Million Readerbase

Table of Contents

Google Scholar citation report
Citations : 378

Analytical Chemistry: An Indian Journal received 378 citations as per Google Scholar report

Indexed In

  • CASS
  • Google Scholar
  • Open J Gate
  • China National Knowledge Infrastructure (CNKI)
  • CiteFactor
  • Cosmos IF
  • Electronic Journals Library
  • Directory of Research Journal Indexing (DRJI)
  • Secret Search Engine Labs
  • ICMJE

View More

Flyer