The fundamental goal of using computer simulation system in the generating process of music creation, is to complete the computer system's perception of music and intelligent creation of music at the information age. Under the current information age, in the field of music, multimedia technology is mainly used on the visual and auditory aspects. And the core of the multimedia technology is the audio technology. In modern society, music has been widely needed in many fields, such as: the film and television industry, stereo audiovisual publishing houses, concerts, and so on. Due to the fact that human energy is limited, the traditional production method of music creation also has some limitations for meeting the demand of music. For the music itself, it mainly comes from nature, and the sound of nature is interrelated with the emotional melody in human sense. In the field of music, sound is made up of four main factors, namely, pitch, amplitude, length and timbre. The orderly combination of these four factors has formed a set of reasonable and orderly computer simulation system of music creation. Note is the most basic unit in a group of wonderful music, the frequency of the sound and the length of the length of notes. That is to say, the computer simulation system has certain uniqueness while using in the generation process of music creation. Meanwhile in today's information age, computer technology has been equipped with mature software and hardware facilities.