Abstract

Evaluation of Anti-inflammatory Activity of Roots of Atalantia monophylla

Author(s): B. Ganga Rao, M. Sanjith Nath, G. V. Sampath Kumar and M. Samuel

The study was designed to evaluate the anti-inflammatory effect of methanolic and chloroform root extracts of Atalantia monophylla (Rutaceae), in carrageenan induced albino wistar rats of either sex (175-225 g).The anti-inflammatory effects of chloroform extract of Atalantia monophylla 200,400 mg/kg p.o were found to be significant in reducing rat paw oedema induced by carrageenan, where as methanolic extract produced significant reduction of paw oedema at 400 mg/kg p.o. Ibuprofen (50 mg/kg) was used as the reference anti-inflammatory agent for comparison. The chloroform extract was highly significant in reducing rat paw oedema. The result of this experimental animal study indicated that the extracts possess anti-inflammatory activity, and thus, lend credence to the suggested use of these plants in the management or control of arthritis and other inflammatory conditions in certain communities of India.


Share this