In painting appreciation course, the multimedia teaching based on computer can change the teaching methods of teacher-centered and one-way indoctrination. To a certain extent, it can reflect the charm and the strong appeal of the painting art. This makes the painting class more vivid and the teaching more intuitive so as to stimulate students' interest in painting lesson. When making the multimedia courseware of painting appreciation, we should elaborate it based on the actual situation and the subject characteristics and adopts the flexible multimedia teaching method to obtain the ideal effect. The practice proves that the effect is very good using multimedia teaching method in painting appreciation course.