44 7460 854 031

All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.

Abstract

Antibacterial and in vivo and in vitro Anti-inflammatory Activity of Some Novel Substituted Thienopyrimidinone

Author(s): Sajal Srivastava and S. Barnali Das

3-Amino-2-mercapto-7-methyl-5, 6, 7, 8-tetrahydropyrido (b) thieno [2, 3-d]pyrimidin-4 (3 H) - ones were prepared by multi component condensation between sulphur, ketone and ethylcyanoacetate adopting Gewald reaction1 and then treatment with carbondi sulphide, DMS and NaOH followed by cyclization with hydrazine hydrate. It was condensed with substituted aryl aldehydes to yield Schiff base. Then, these Schiff bases were tested for anti-inflammatory and antibacterial activity.


Share this       
Google Scholar citation report
Citations : 9398

International Journal of Chemical Sciences received 9398 citations as per Google Scholar report

Indexed In

  • Google Scholar
  • Open J Gate
  • China National Knowledge Infrastructure (CNKI)
  • Cosmos IF
  • Geneva Foundation for Medical Education and Research
  • ICMJE

View More