Amniotic band sequence refers to a highly variable spectrum of congenital anomalies that occur in association with amniotic bands. The pathogenesis of amniotic band syndrome is not firmly established. Clinical features are variable and include amniotic band adhesion, placental adhesions, craniofacial clefting, amputation, ring constriction, thoraco abdomino schisis and internal malformations. We report a newborn presented at birth with multiple constriction rings, partial amputation, syndactyly, cleft palate,malformed nose and bilateral micro-opthalmia. These findings were suggestive of amniotic band disruption complex.