Hyperlipidemia - Prevalence And Prediction Of Risk For Coronary Heart Disease In A South Indian Population
 

Vasantha Janardhan^*, Kannan Gopal, Vanitha Rani, Thennarasu Palani,
Uma Maheswara Reddy Cheekala
Department of Pharmacy Practice, Sri Ramachandra College of Pharmacy,
Sri Ramachandra University, Chennai - 600 116, Tamilnadu, (INDIA)

Hyperlipidemia is one of the major risk factor for coronary heart disease (CHD); a major leading cause of mortality and thus the study of prevalence of hyperlipidemia and the risk prediction for coronary heart disease were important and timely. A prospective study was carried out in 397 subjects who registered for Master Health Check-Up program in a tertiary care teaching hospital. There were 245 males (mean age 49.59±12.81) and 152 females (mean age 49.13 ± 10.60). The incidence of hyperlipidemia was determined as per NCEP ATP III guidelines. The prevalence of abnormal serum lipid levels was more prominent in the age group of 40-59 years in both the sexes. High levels of triglycerides were identified in 41.5% and very high levels in 1.2%; LDL- cholesterol levels were high in 32.9% and very high in 7.45%, and a higher total cholesterol levels were found in 25.35%. HDL- cholesterol levels were found to be low in 34.35%. The 10-year risk prediction for coronary artery disease was done using Framingham coronary risk prediction algorithm scale which uses Total cholesterol and LDL-C levels. Based on LDL levels, 59% of the study population had <10% risk, 28% were in the 10-20% risk category and 13% had >20% risk. Based on total cholesterol levels, 57 % had <10% risk.31 % were under 10-20% risk category and 12% had >20% risk. The risk may be doubled in South Asian population.