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Research
& Reviews
in
BioSciences |
June 2009
Volume 3(1) |
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Serum Lipid Profile Of Type-2
Diabetic Patients In
The Dhaka City Of Bangladesh
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Bidhan Chandra Sarkar, Niranjan Kumar Sana*, Goutam Kumar
Sarker,
Ranajit Kumar Shaha
Department of Biochemistry and Molecular Biology, University of
Rajshahi,
Rajshahi-6205, (BANGLADESH) |
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Serum lipid profile viz the
level of total cholesterol (TC), Triglyceride (TG), HDL-cholesterol and
LDL-cholesterol of type-2 diabetic patients have been studied and
compares them with levels of control subjects. The mean value of the TG
level for male diabetics was higher than that for the female diabetics
and the mean values of TC, HDL-C and LDL-C were not found significantly
difference between male and female diabetics. Hyperlipidemia has a
documented causative relation with CAD, but the major risk associated
with diabetes may be due to the associated hyperlipidemia. The study
revealed that dyslipidemia is very common in type-2 diabetics and the
most common abnormality observed was increased serum triglyceride (58%)
levels. The next common abnormality was decreased serum high-density
lipoprotein cholesterol (HDL-C) levels and increased serum low-density
lipoprotein cholesterol (LDL-C) levels. A high total serum cholesterol
levels was found in 41% patients. 39% of the patients examined were on
the overweight side, 7% being overly obese. Thus the study clearly shows
the relation between type-2 diabetes and hyperlipidemia, which may
influence the mechanism by which type-2 diabetes is associated with
increased CAD risk. |
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